Freezing, Heating and Some Factors Affecting Immune Response Induced by Inactivated Vaccines in Broiler Chickens

Document Type : Original Article

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Abstract

Poultry vaccines should have a specific storage temperature range to ensure their
effectiveness. It is still unclear in Egypt, nevertheless, if these temperature ranges are
rigidly specified as handling conditions or as recommendations. Large endemic and
epidemic outbreaks of poultry illnesses frequently threaten Egypt's sizable conventional
and exotic chicken industries. Although it is assumed in vaccine logistics that most of these
safety measures are followed, handling vaccines within the specified temperature range is
frequently not feasible. It is challenging to keep vaccines within a designated storage
temperature range when they are being transported, according to earlier research. This is
an issue not just in nations with weak cold chains but also in nations and areas with strong
cold chains. Specifically, the chance of unintentionally being exposed to below-freezing
conditions has been disregarded globally. This is a serious concern for vaccination
consumers as well as the veterinarians who oversee vaccine usage. Because they cannot
ensure the quality of vaccines whose storage temperature may have been beyond the
prescribed range, veterinarians should advise consumers not to vaccinate birds with these
vaccines. Additionally, the user is directly harmed in the uncommon case that a handling
error impairs the quality of the vaccination.

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Journal of Current Veterinary Research
Volume 6, Issue 1
April 2024
Pages 253-271

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