A review on Clostridium perfringens toxins with special reference to Beta 2 toxin

Document Type : Original Article

Author

Department of animal medicine and infectious diseases - Faculty of veterinary medicine - University of Sadat City- Egypt.

Abstract

Clostridium perfringens toxins are the main cause of lesions and symptoms associated with diseases caused by its infection. There are two main groups of toxins; major and minor. The major toxins are alpha (CPA), beta (CPB), epsilon (ETX), and iota (ITX) toxins. Theses toxins are lethal and necrotizing agents. minor toxins such as eta, theta (θ), kappa, lambda, mu, nu toxins, neuraminidase, sialidase, enterotoxin, non-alpha-delta-theta hemolysin, and metabolic active substance. Recently there are newly discovered toxins Such as enterotoxin and a cytotoxic beta -2 toxin. Theses toxins may play an important role in pathogenesis of the diseases and need more investigation. Here we summarized important data about Clostridium perfringens toxins.

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